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Antigenic Specificity | Mouse CD49e |
Clone | [5H10-27 (MFR5] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: alpha 5 subunit of the integrin alpha 5 beta 1 fibronectin receptor. The monoclonal antibody 5H10-27 reacts with the alpha 5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines.^1-5 Soluble 5H10-27 antibody inhibits VLA-5-mediated functions in vitro.^1, 2-4, 6 Immobilized 5H10-27 has also been demonstrated to co-stimulate the proliferative response of CD8^+ T cells to plate-bound anti- CD3 monoclonal antibody.^3. |
Immunogen | Immunogen: C57BL/6 x A/J F1 mouse mast cell line MC/9 1 |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS673404 |
Price | $280 |
Order / More Info | Mouse CD49e Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kinashi, T., and T.A. Springer. 1994. Blood Cells 20:25.2. Halvorson, M.J., and J.E. Coligan. 1995. J. Immunol. 155:4567.3. Rich, S., N. van Nood, and H.-M Lee. 1996. J. Immunol. 157:2916.4. Uhlenkott, C.E., J.C. Huijzer, D.J. Cardeiro, C.A. Elstad, and G.G. Meadows. 1996. Clin. Exp. Metastasis 14:125.5. Hemler, M.E. 1990. Annu. Rev. Immunol. 8:365.6. Schultz, J.F., and D.R. Armant. 1995. J. Biol Chem. 270:11522. |