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Antigenic Specificity | IL-17A |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b/k |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 0.5 mg/mL solution |
Applications | Western Blot (WB), ELISA (EIA), Neutralization of Human IL-17A activity (NIH3T3 Assay) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukin-17A (IL-17A), also known as CTLA-8, is a pro-inflammatory cytokine member of a six-species family of proteins (IL-17A-17F). IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most importantly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. |
Immunogen | Immunogen: Full length recombinant Human IL-17A. Endotoxin level: <0.1 EUs/ug |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS689608 |
Price | $310 |
Order / More Info | IL-17A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |