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Antigenic Specificity | PJA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PJA1 antibody detects endogenous levels of total PJA1. Function: Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting.Subunit Structure: Binds ubiquitin-conjugating enzymes (E2s). In vitro, interacts with the ubiquitin-conjugating enzyme, UBE2D2.Post-translational Modifications: Substrate for E2-dependent ubiquitination.Similarity: The RING-type zinc finger domain interacts with an ubiquitin-conjugating enzyme (E2) and facilitates ubiquitination. |
Immunogen | Immunogen: A synthesized peptide derived from human PJA1 Tissue Specificity: Expressed in various regions of the brain including the cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Highest levels in the cerebral cortex. |
Other Names | [E3 ubiquitin-protein ligase Praja-1 isoform b; E3 ubiquitin-protein ligase Praja-1; E3 ubiquitin-protein ligase Praja-1; praja ring finger ubiquitin ligase 1; RING finger protein 70; RING-type E3 ubiquitin transferase Praja-1Curated] |
Gene, Accession # | [PJA1], Gene ID: 64219, NCBI: NP_001027568.1, UniProt: Q8NG27 |
Catalog # | MBS9609804 |
Price | $240, $280 |
Order / More Info | PJA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |