Human-PIK3R2(Y464) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman-PIK3R2(Y464)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.05 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 430-470 amino acids from human. Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5- trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regula
Immunogenn/a
Other Names[Purified Rabbit (Pab); Phosphatidylinositol 3-kinase regulatory subunit beta; PI3-kinase regulatory subunit beta; PI3K regulatory subunit beta; PtdIns-3-kinase regulatory subunit beta; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; PI3-kinase subunit p85-beta; PtdIns-3-kinase regulatory subunit p85-beta; PIK3R2]
Gene, Accession #[PIK3R2], Gene ID: 5296, NCBI: NP_005018.1, UniProt: O00459
Catalog #MBS9215922
Price$150
Order / More InfoHuman-PIK3R2(Y464) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesVolinia S.,et al.Oncogene 7:789-793(1992).Janssen J.W.G.,et al.Oncogene 16:1767-1772(1998).Grimwood J.,et al.Nature 428:529-535(2004).Braunger J.,et al.Oncogene 14:2619-2631(1997).Igarashi K.,et al.Biochem. Biophys. Res. Commun. 246:95-99(1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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