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Antigenic Specificity | PDZK1 (Center), 196-224 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PDZK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human PDZK1. A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and |
Immunogen | n/a |
Other Names | [Na(+)/H(+) exchange regulatory cofactor NHE-RF3; NHERF-3; CFTR-associated protein of 70 kDa; Na(+)/H(+) exchanger regulatory factor 3; Na/Pi cotransporter C-terminal-associated protein 1; NaPi-Cap1; PDZ domain-containing protein 1; Sodium-hydrogen exchanger regulatory factor 3; PDZK1; CAP70; NHERF3; PDZD1] |
Gene, Accession # | [PDZK1], Gene ID: 5174, NCBI: NP_001188254.1, UniProt: Q5T2W1 |
Catalog # | MBS9212114 |
Price | $165, $370 |
Order / More Info | PDZK1 (Center), 196-224 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) LaLonde, D.P., et al. Mol. Biol. Cell 21(9):1519-1529(2010) Polasek, O., et al. Croat. Med. J. 51(1):32-39(2010) Gunjaca, G., et al. Croat. Med. J. 51(1):23-31(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) |