ZAP70 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ZAP70 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.05 mg |
| Concentration | 1ug/ul |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ZAP70 (zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Zap70 controls TCR (T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the zap-70 gene. ZAP-70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia. |
| Immunogen | Immunogen: Ni-NTA purified truncated recombinant ZAP70 expressed in E Coli strain BL21 (DE3) |
| Other Names | [ZAP70 protein; Tyrosine-protein kinase ZAP-70; tyrosine-protein kinase ZAP-70; zeta chain of T-cell receptor associated protein kinase 70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase], [ZAP70; ZAP70; SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70; SRK] |
| Gene, Accession # | [ZAP70], Gene ID: 7535, NCBI: AAH39039.1 |
| Catalog # | MBS418414 |
| Price | $445 |
| Order / More Info | ZAP70 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1.Sigal Gelkop, Gerrald D. Gish, Yael Babichev J Immunol. 2005 Dec 15;175 (12):8123-32 2.Joaquim Carreras, Neus Villamor, Lluis Colomo J Pathol. 2005 Mar;205 (4):507-13 3.Claire Hivroz Med Sci (Paris). 2005 Feb;21 (2):150-5 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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