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Antigenic Specificity | Human TAB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: synthetic peptide corresponding to 13 amino acids in the center of human TAB1. TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF-b and members of the Toll-IL-1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. |
Immunogen | Immunogen Description: Synthetic peptide from human TAB1 / MAP3K7IP1. |
Other Names | [TAB1 IHC-plus; TAB1; 3'-Tab1; 3-Tab1; MAP3K7IP1; TAK1-binding protein 1; Human TAB1], [TAB1; TAB1; 3'-Tab1; MAP3K7IP1; MAP3K7IP1; TAK1-binding protein 1] |
Gene, Accession # | [TAB1], Gene ID: 10454, NCBI: NP_006107.1, UniProt: Q15750 |
Catalog # | MBS240335 |
Price | $530 |
Order / More Info | Human TAB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |