LGR6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLGR6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Flow Cytometry (FC/FACS)
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DescriptionSpecificity: Human, Mouse,Rat; other species are not tested. Please decide the specificity by homology. Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
ImmunogenImmunogen: leucine-rich repeat-containing G protein-coupled receptor 6
Other Names[FLJ14471, GPCR, LGR6, VTS20631]
Gene, Accession #[LGR6], Gene ID: 59352, NCBI: NP_001017404.1, UniProt: Q9HBX8
Catalog #MBS7600999
Price$265
Order / More InfoLGR6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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