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Antigenic Specificity | FCN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. |
Immunogen | Immunogen: Recombinant human Ficolin-1 protein (30-326AA) |
Other Names | [Ficolin-1; Collagen/fibrinogen domain-containing protein 1; Ficolin-A; Ficolin-alpha; M-ficolin; FCN1; FCNM] |
Gene, Accession # | [FCN1], Gene ID: 2219, NCBI: NP_001994.2, UniProt: O00602 |
Catalog # | MBS7043777 |
Price | $120, $160 |
Order / More Info | FCN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |