Phospho-EP300 (S1834) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-EP300 (S1834)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationn/a
ApplicationsDot Blot (DB), ELISA (EIA)
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DescriptionThis EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human EP300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of
Immunogenn/a
Other Names[Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300; EP300; P300]
Gene, Accession #[EP300], Gene ID: 2033, NCBI: NP_001420.2, UniProt: Q09472
Catalog #MBS9213944
Price$165, $370
Order / More InfoPhospho-EP300 (S1834) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesZhang, M., et al. J. Immunol. 185(7):3960-3969(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Vempati, R.K., et al. J. Biol. Chem. 285(37):28553-28564(2010) Reynoird, N., et al. EMBO J. 29(17):2943-2952(2010) Jang, E.R., et al. Biochem. Biophys. Res. Commun. 397(4):637-643(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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