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Antigenic Specificity | Mouse 4-1BB receptor |
Clone | [4G33] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects mouse 4-1BB in Western blots. 4-1BB, also known as CD137 and ILA (induced by lymphocyte activation), is a TNF receptor superfamily member and has been designated TNFRSF9. Mouse 4-1BB cDNA encodes a 256 amino acid (aa) residues type I transmembrane protein with a putative 23 aa signal peptide, a 164 aa extracellular domain, a 21 aa transmembrane domain and a 48 aa cytoplasmic region. A soluble 4-1BB is released from surfaces of cells expressing the transmembrane protein. Mouse4-1BB shares approximately 60% aa sequence identity with its human counterpart. 41BB is expressed on activated CD4+ and CD8+ T cells, thymocytes, and NK cells. It is also expressed on monocytes, neutrophils, DCs and eosinophils. The ligand for 4-1B |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant 4-1BB extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
Other Names | [mouse 4-1BB [TNFRSF9] (#4G33)], [Tnfrsf9; Tnfrsf9; ILA; Ly63; 4-1BB; Cd137; CDw137; AA408498; AI325004; A930040I11Rik; Cd137; Ila; Ly63] |
Gene, Accession # | [4-1BB receptor], Gene ID: 21942, NCBI: NP_001070977.1, UniProt: P20334 |
Catalog # | MBS690773 |
Price | $490 |
Order / More Info | Mouse 4-1BB receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |