Collagen XXV alpha1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Collagen XXV alpha1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Collagen XXV alpha1 antibody detects endogenous levels of total Collagen XXV alpha1. Function: Inhibits fibrillization of amyloid-beta peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin.Subunit Structure: Forms homodimers and homotrimers. Binds to the fibrillized forms of amyloid-beta protein 40 (beta-APP40) and amyloid-beta protein 42 (beta-APP42). Found associated with beta-APP42 more frequently than with beta-APP40.Post-translational Modifications: Undergoes proteolytic cleavage by furin protease to yield the soluble collagen-like Alzheimer amyloid plaque component. Glycosylated. Hydroxylated on 11% of proline residues and 49% of lysi |
| Immunogen | Immunogen: A synthesized peptide Tissue Specificity: Expressed predominantly in brain. Deposited preferentially in primitive or neuritic amyloid plaques which are typical of Alzheimer disease. Predicted Cross Reactivity: Pig, Rabbit Similarity: Pig (100%), Rabbit (100%) |
| Other Names | [Alzheimer disease amyloid associated protein; Alzheimer disease amyloid-associated protein; AMY; CLAC; CLAC P; CLAC precursor; CLAC-P; Col25a1; COL25A1 protein; Collagen alpha 1 XXV chain; Collagen alpha 1(XXV) chain; Collagen like Alzheimer amyloid plaque component; Collagen like Alzheimer amyloid plaque component precursor; Collagen type XXV alpha 1; Collagen-like Alzheimer amyloid plaque component; Collagenous Alzheimer amyloid plaque component; COPA1_HUMAN] |
| Gene, Accession # | [COL25A1], Gene ID: 84570, NCBI: NP_115907.2, UniProt: Q9BXS0 |
| Catalog # | MBS9605013 |
| Price | $240, $280 |
| Order / More Info | Collagen XXV alpha1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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