EZH2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEZH2
Clone[1F10A12]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatProtein A purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionEZH2 (enhancer of zeste homologue 2, also known as KMT6) is a member of Polycomb group (PcG) family and encodes a histone methyl transferase that has an essential role in promoting histone H3 lysine 27 trimethylation (H3K27me3) and epigenetic gene silencing. EZH2 is important for cell proliferation and inhibition of cell differentiation, and is implicated in cancer progression. Overexpression of EZH2 is a marker of advanced and metastatic disease in many solid tumors, including prostate and breast cancer. This antibody detected EZH2 protein as a single band with a molecular weight (MW) of 91-100 kDa in multiple cell lines. The phosphorylation may result in the higher molecular weight (calculated MW as 80-86 kDa). (20935635, 21367748)
ImmunogenImmunogen: Fusion protein of EZH2 Buffer: PBS with 0.1% sodium azide, 50% glycerol, PH7.3 Conjugation: Unconjugated
Other Names[Enhancer of zeste homolog 2; ENX 1; EZH1; EZH2; KMT6; Lysine N methyltransferase 6]
Gene, Accession #[EZH2], Gene ID: 2146, NCBI: BC010858, UniProt: Q15910
Catalog #MBS2549072
Price$220, $290, $435
Order / More InfoEZH2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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