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Antigenic Specificity | alpha-Tubulin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: alpha-Tubulin antibody is human, mouse and rat reactive. alpha-Tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-Tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter (reviewed in 1). Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-Tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase (2). Another post-translational modification |
Immunogen | Immunogen: alpha-Tubulin antibody was raised against an 18 amino acid peptide near the carboxy terminus of human alpha-Tubulin. Buffer: alpha-Tubulin antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Tubulin alpha-1A; TUBA1A; TUBA3; LIS3; tubulin, alpha 1a], [TUBA1A; TUBA1A; LIS3; TUBA3; B-ALPHA-1; TUBA3] |
Gene, Accession # | [TUBA1A], Gene ID: 7846, NCBI: CAA25855, UniProt: Q71U36 |
Catalog # | MBS154440 |
Price | $375 |
Order / More Info | alpha-Tubulin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. McKean PG, Vaughan S, and Gull K. The extended tubulin family. J. Cell Sci. 2001; 114:2723-33. 2. Barra HA, Arce CA, and Argarana CE. Posttranslational tyrosination/detyrosination of tubulin. Mol. Neurobiol. 1988; 2:133-53. 3. Fukshima N, Furuta D, Hidaka Y, et al. Post-translational modifcations of tubulin in the nervous system. J. Neurochem. 2009; 109:683-693. |