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Antigenic Specificity | Human Galectin-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine |
Immunogen | Immunogen: recombinant human Galectin-1 (RT #100-175). Preparation: Produced from sera of rabbits pre-immunized with highly pure (>95%) recombinant human Galectin-1 (Ala2-Asp135) derived from E. coli. |
Other Names | [human Galectin-1; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; S-Lac lectin 1], [LGALS1; LGALS1; GBP; GAL1; Gal-1; HLBP14] |
Gene, Accession # | Gene ID: 3956, NCBI: NP_002296.1, UniProt: P09382 |
Catalog # | MBS691064 |
Price | $280 |
Order / More Info | Human Galectin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Rabinovich A et al, Trends in Immunol 23:313, 2002 2. Rabinovich A et al, J Leukocyte Biology 71:741, 2002 3. Hughes RC, Biochimie 83:667, 2001 |