Tau (Ab-534/217) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Tau (Ab-534/217) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total Tau protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.Goedert M.,Proc. Natl. Acad. Sci. U.S.A. 85:4051-4055(1988).Goedert M., EMBO J. 8:393-399(1989).Lee G., Neuron 2:1615-162 |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized non-phosphopeptide derived from human Tau around the phosphorylation site of threonine 534/217 (L-P-T(p)-P-P). |
| Other Names | [MAPT; Microtubule-associated protein tau; MTBT1; Neurofibrillary tangle protein; Paired helical filament-tau] |
| Gene, Accession # | [Tau], Gene ID: 4137, NCBI: NP_001116538.2, UniProt: P10636 |
| Catalog # | MBS9405104 |
| Price | $200, $255 |
| Order / More Info | Tau (Ab-534/217) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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