Edit |   |
---|---|
Antigenic Specificity | HXK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total HXK1 protein. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human HXK1. |
Other Names | [Hexokinase-1; EC 2.7.1.1; Hexokinase type I; HK I; Brain form hexokinase] |
Gene, Accession # | [HXK1], Gene ID: 3098, NCBI: NP_000179.2, UniProt: P19367 |
Catalog # | MBS9401480 |
Price | $200, $255 |
Order / More Info | HXK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |