CDK11 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CDK11 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CDK11 antibody detects endogenous levels of total CDK11. Function: Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.Subunit Structure: The cleaved p110 isoform, p110C, binds to the serine/threonine kinase PAK1. The p58 isoform but not the p110 isoform or p110C interacts with CCND3. The p110 isoforms are found in large molecular weight complexes containing CCNL1 and SFRS7.Post-translational Modifications: During apoptosis, induced by Fas or tumor necrosis factor, specific CK |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Expressed ubiquitously. Some evidence of isoform-specific tissue distribution. |
| Other Names | [CD11A_HUMAN; CDC2L2; CDC2L3; CDK11; CDK11 p110; CDK11 p46; CDK11 p58; CDK11A; Cell division cycle 2 like 2 (PITSLRE proteins); Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Cyclin-dependent kinase 11A; Galactosyltransferase-associated protein kinase p58/GTA; p58GTA; PITSLRE; PITSLRE B; PITSLRE protein kinase beta; PITSLRE serine/threonine-protein kinase CDC2L2; PITSLREB; CDC2L1; CDK11; Cell division cycle 2-like protein kinase 1; Cell division protein kinase 11B; CLK 1; EC=2.7.11.22; Galactosyltransferase associated protein kinase p58/GTA; ITSLRE serine/threonine protein kinase CDC2L1; p58 CLK 1; PITSLREA; PK58] |
| Gene, Accession # | [CDK11], Gene ID: 728642, NCBI: NP_001300825.1, UniProt: Q9UQ88 |
| Catalog # | MBS9604933 |
| Price | $240, $280 |
| Order / More Info | CDK11 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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