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Antigenic Specificity | MALT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MALT1 antibody is human, mouse and rat reactive. At least two isoforms of MALT1 are known to exist; this antibody will detect both isoforms. MALT1 was initially identified as a novel gene that was recurrently rearranged in t(11;18)(q21;q21) mucosa-associated lymphoid tissue lymphomas along with the apoptosis inhibitor protein c-IAP2 (1). MALT1, along with the proteins CARMA1 and Bcl10 form an NF-kappaB-activating complex, termed the CBM signalsome, that acts downstream of lymphocyte antigen receptors as well as many other non-lymphoid cell-surface receptors that play a role in multiple cellular functions (2,3). MALT1 has proteolytic activity, and this activity is critical for full NF-kappaB response in T cell activation (4). |
Immunogen | Immunogen: MALT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MALT1. Buffer: MALT1 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Mucosa associated lymphoid tissue lymphoma translocation 1; IMD12; MLT; MLT1; mucosa associated lymphoid tissue lymphoma translocation gene 1], [MALT1; MALT1; MLT; MLT1; IMD12; MLT] |
Gene, Accession # | [MALT1], Gene ID: 10892, NCBI: NP_006776, UniProt: Q9UDY8 |
Catalog # | MBS153417 |
Price | $375 |
Order / More Info | MALT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |