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Antigenic Specificity | Human CD234 (C-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | reacts with: mouse, rat. |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD234 (C-Terminal). This item detects CD234, also known as DARC, a multi-pass membrane protein belonging to the G protein coupled Duffy family. CD234 is a non-specific receptor for a number of cytokines including IL-8, GRO, RANTES, MCP-1 and TARC. CD234 also functions as the receptor for the malaria parasites Plasmodium vivax and P. knowlesi. CD234 is also responsible for the Duffy blood group system where a substitution at position 42 of either Gly-42 or Asp-42 results in Fy(A) or Fy(B). CD234 is present in adult kidney, adult spleen, bone marrow and fetal liver. In particular, it is expressed along post capillary venules throughout the body, except in the adult liver. Erythroid cells and post capillary venule endothelium are |
Immunogen | Immunogen: A peptide corresponding to a 16 amino acid sequence from near the carboxy terminus of Human CD234. Histology Positive Control Tissue: Mouse brain tissue Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to Human CD234 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [atypical chemokine receptor 1 isoform a; Atypical chemokine receptor 1; atypical chemokine receptor 1; Duffy blood group antigen; Duffy blood group, atypical chemokine receptor; Duffy blood group, chemokine receptor; Fy glycoprotein; glycoprotein D; plasmodium vivax receptor; atypical chemokine receptor 1 (Duffy blood group); Duffy antigen/chemokine receptor; Fy glycoprotein; GpFy; Glycoprotein D; Plasmodium vivax receptor; CD_antigen: CD234], [ACKR1; ACKR1; FY; Dfy; GPD; DARC; GpFy; CCBP1; CD234; WBCQ1; DARC; FY; GPD; GpFy] |
Gene, Accession # | [CD234], Gene ID: 2532, NCBI: NP_001116423.1, UniProt: Q16570 |
Catalog # | MBS223703 |
Price | $375 |
Order / More Info | Human CD234 (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |