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Antigenic Specificity | Human GRM3 / MGLUR3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Gibbon, bovine, gorilla, hamster, horse, human, monkey, mouse, orangutan, porcine, rat. predicted reactivity: rabbit, chicken (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human GRM3 / MGLUR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins. The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade. |
Immunogen | Immunogen Description: Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GRM3 / MGLUR3. |
Other Names | [GRM3 / MGLUR3 (N-Terminus) IHC-plus; GRM3; GPRC1C; GLUR3; MGLUR3; MGlu3; Human GRM3; MGLUR3], [MGLUR3] |
Gene, Accession # | [GRM3], Gene ID: 2913, NCBI: NP_000831.2, UniProt: Q14832 |
Catalog # | MBS246895 |
Price | $530 |
Order / More Info | Human GRM3 / MGLUR3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |