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Antigenic Specificity | TRADD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.54 mg/ml |
Applications | Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. |
Immunogen | Immunogen: TRADD antibody was raised in rabbit using a synthetic peptide corresponding to a region within amino acids 1 and 43 of TRADD |
Other Names | [Affinity Purified Rabbit TRADD; TRADD; TRADD; MGC11078; tumor necrosis factor receptor type 1 associated death domain protein; TRADD; Hs.89862; tumor necrosis factor receptor-1-associated protein; tumor necrosis factor receptor type 1-associated DEATH domain protein] |
Gene, Accession # | [TRADD], Gene ID: 8717, UniProt: Q15628 |
Catalog # | MBS5311969 |
Price | $485 |
Order / More Info | TRADD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |