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Antigenic Specificity | Mouse CD3 |
Clone | [3B19] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The T cell receptor (TCR)/CD3 complex consists of two variable antigen-recognition receptor chains (TCR-alpha/TCR-beta or TCR-gamma/TCR-delta) that are non-covalently linked to at least four different invariant chains: CD3 gamma, CD3 delta, CD3 epsilon, and the CD3 zeta chain that exists as either a homodimer or as a heterodimer with its splice-variant the CD3 eta chain. The CD3 complex functions to transduce intracellular signals during TCR antigen recognition. CD3 is expressed early in thymocyte development, and on a subset of NK cells. CD3 epsilon is one of at least three invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with CD3 positive mouse T-Cells. IgG2b fraction of the culture supernatant was purified by Protein G affinity chromatography.. Antigen: mouse CD3 positive cells |
Other Names | [mouse CD3 (T-Cell marker)], [Cd247; Cd247; Cd3; T3z; Cd3h; Cd3z; Tcrk; Tcrz; Cd3-eta; Cd3zeta; AW552088; Cd3-zeta; 4930549J05Rik; A430104F18Rik; Cd3z; Tcrz] |
Gene, Accession # | [CD3], Gene ID: 12503, NCBI: NP_001106862.1, UniProt: P24161 |
Catalog # | MBS690806 |
Price | $490 |
Order / More Info | Mouse CD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |