NOD1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNOD1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionNod1/CARD4 is a cytosolic protein structually related to Apaf-1 and plant drug-resistance proteins that has been implicated in apoptosis and inflammatory responses to certain pathogenic bacteria (1-3). It contains an amino-terminal caspase recruitment domain (CARD) that is linked to a central nucleotide-binding domain (NBD; also known as a NOD domain) and is followed by carboxy-terminal leucine-rich repeats (LRR) (1). Like Apaf-1, Nod1 induces apoptosis by a CARD/NBD-dependent activation of caspase-9 (1). The primary function of Nod1 is thought to be as a sensor for certain pathogenic microbes and triggering inflammatory responses including the activation of NF-kappaB and JNK pathways (4-6). The LRR of Nod1 appears to be involved in recogni
ImmunogenImmunogen: Recombinant Protein
Other Names[NOD1; CARD4; CLR7.1; NLRC1], [NOD1; NOD1; CARD4; NLRC1; CLR7.1; CARD4]
Gene, Accession #[NOD1], Gene ID: 10392, NCBI: Q9Y239.1, UniProt: Q9Y239
Catalog #MBS128101
Price$200, $275, $430
Order / More InfoNOD1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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