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Antigenic Specificity | BID |
Clone | [4D3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases. |
Immunogen | Immunogen: Recombinant human BID (1-195aa) purified from E. coli |
Other Names | [BH3 interacting domain death agonist isoform 2; FP497; MGC15319; MGC42355; BH3 interacting domain death agonist isoform 2; BID; BH3 interacting domain death agonist isoform 2 Apoptotic death agonist; Apoptotic death agonist BID; BH3 interacting domain death agonist; HGNC:1050; BH3 interacting domain death agonist p11; BH3 interacting domain death agonist p13; BH3 interacting domain death agonist p15; BID isoform ES (1b); BID isoform L (2); Desmocollin type 4; Human BID coding sequence; OTTHuMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID.], [BID; BID; FP497; BID] |
Gene, Accession # | [BID], Gene ID: 637, NCBI: NP_001187, UniProt: P55957 |
Catalog # | MBS200123 |
Price | $240, $315 |
Order / More Info | BID Antibody from MYBIOSOURCE INC. |
Product Specific References | Zha J., et al. (2000) Science. 290:1761; Luo X., et al. (1998) Cell. 94:481; Li H., et al. (1998) Cell. 94:491 |