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Antigenic Specificity | PAK4 (N-term), 156-187 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-187 amino acids from the N-terminal region of human PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin |
Immunogen | n/a |
Other Names | [Serine/threonine-protein kinase PAK 4; p21-activated kinase 4; PAK-4; PAK4; KIAA1142] |
Gene, Accession # | [PAK4], Gene ID: 10298, NCBI: NP_001014831.1, UniProt: O96013 |
Catalog # | MBS9207169 |
Price | $165, $370 |
Order / More Info | PAK4 (N-term), 156-187 Antibody from MYBIOSOURCE INC. |
Product Specific References | Lu, Y., et al., J. Biol. Chem. 278(12):10374-10380 (2003). Bagrodia, S., et al., Trends Cell Biol. 9(9):350-355 (1999). Abo, A., et al., EMBO J. 17(22):6527-6540 (1998). |