PAK4 (N-term), 156-187 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPAK4 (N-term), 156-187
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis PAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-187 amino acids from the N-terminal region of human PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin
Immunogenn/a
Other Names[Serine/threonine-protein kinase PAK 4; p21-activated kinase 4; PAK-4; PAK4; KIAA1142]
Gene, Accession #[PAK4], Gene ID: 10298, NCBI: NP_001014831.1, UniProt: O96013
Catalog #MBS9207169
Price$165, $370
Order / More InfoPAK4 (N-term), 156-187 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLu, Y., et al., J. Biol. Chem. 278(12):10374-10380 (2003). Bagrodia, S., et al., Trends Cell Biol. 9(9):350-355 (1999). Abo, A., et al., EMBO J. 17(22):6527-6540 (1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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