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Antigenic Specificity | E2F3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Transcription factor E2F3(E2F3) detection. Background: Transcription factor E2F3, also known as KIAA0075, is a protein that in humans is encoded by the E2F3 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. By fluorescence in situ hybridization, E2F3 gene is mapped to 6q22.3. The induction of specific E2F activities is an essential component in the MYC pathways that control cell proliferation and cell fate decisions. This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma pr |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human E2F3 (278-320aa QSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKA), identical to the related mouse sequence. |
Other Names | [E2F3; E2F-3; KIAA0075; Transcription factor E2F3; O00716; E2F transcription factor 3], [E2F3; E2F3; E2F-3; KIAA0075; E2F-3] |
Gene, Accession # | [E2F3], Gene ID: 1871, NCBI: NP_001230005.1, UniProt: O00716 |
Catalog # | MBS178679 |
Price | $280 |
Order / More Info | E2F3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Chen, D., Pacal, M., Wenzel, P., Knoepfler, P. S., Leone, G., Bremner, R. Division and apoptosis of E2f-deficient retinal progenitors. Nature 462: 925-929, 2009.2. Chong, J.-L., Wenzel, P. L., Saenz-Robles, M. T., Nair, V., Ferrey, A., Hagan, J. P., Gomez, Y. M., Sharma, N., Chen, H.-Z., Ouseph, M., Wang, S.-H., Trikha, P., and 10 others. E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells. Nature 462: 930-934, 2009. |