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Antigenic Specificity | Vimentin |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human, cow, pig, mouse, rat and other mammals. Vimentin is a Along with the microfilaments (actins) and microtubules (tubulins), the intermediate filaments represent a third class of well-characterized cytoskeletal elements. The subunits display a tissue-specific pattern of expression. Desmin (125660) is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue. |
Immunogen | Immunogen: Vimentin is a protein subunit of 10nm or intermediate filaments, which are major components of the cytoskeleton in most cell types. Vimentin is the major intemediate filament subunit found in mesenchymal cells, and was first named and characterized in a collaborative study from the labs of German scientists Werner Franke and Klaus Weber (1). The name derives from the Latin Vimentum, meaning arrays of flexible rods such as in lattices, filigrees and wicker-work, which describes the i |
Other Names | [Vimentin], [VIM; VIM; CTRCT30] |
Gene, Accession # | Gene ID: 7431, NCBI: NP_003371.2, UniProt: P08670 |
Catalog # | MBS415119 |
Price | $370 |
Order / More Info | Vimentin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Franke, W. W., Schmid, E., Osborn, M. and Weber, K. Different intermediate-sized filaments distinguished by immunofluorescence microscopy. Proc. Natl. Acad. Sci. USA 75:5034-5038 (1978).2. Muller, M., Bhattacharya, S. S., Moore, T., Prescott, Q., Wedig, T., Herrmann, H., Magin, T. M. Dominant cataract formation in association with a vimentin assembly disrupting mutation. Hum. Molec. Genet. 18:1052-1057 (2009). |