Mitochondrial Fission Factor (MFF) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mitochondrial Fission Factor (MFF) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | bovine, human, mouse |
| Isotype | n/a |
| Format | serum |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Specific for endogenous levels of the ~38 kDa Mff protein. Mitochondrial fission factor, also known as Mff, is a tail-anchored, outer mitochondrial membrane protein that is part of a complex process controlling mitochondrial and peroxisomal fission in conjunction with Drp1 and Fis1 (Schrader and Yoon, 2007). The rate of mitochondrial fission and fusion balance each other for cell growth and survival of mitochondria. Fission can be greatly accelerated when cytochrome c is released during apoptosis (Desagher and Martinou, 2000). Mff was identified as an important component of the process through siRNA transfected cells, isolating the protein in the P2 pellet and demonstrating that Mff is exposed to the cytosol (GandreBabbe and va |
| Immunogen | Immunogen Species: Human. Immunogen Information: Human recombinant protein. |
| Other Names | [mitochondrial fission factor isoform a; Mitochondrial fission factor; mitochondrial fission factor; mitochondrial fission factor], [MFF; MFF; EMPF2; GL004; C2orf33; C2orf33; AD030; AD033; GL004] |
| Gene, Accession # | [MFF], Gene ID: 56947, NCBI: NP_001263990.1, UniProt: Q9GZY8 |
| Catalog # | MBS500079 |
| Price | $315 |
| Order / More Info | Mitochondrial Fission Factor (MFF) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Gandre-Babbe S, van der Bliek AM. The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammaliam Cells. Mol Biol Cell 19(6):2402-12 (2008). 2. Desagher s, Martinou JC. Mitochondria as the central control point of apoptosis. Trends Cell Biol 10(9): 369-377 (2000). 3. Schrader M, Yoon Y. Mitochondria and peroxisomes: are the 'big brother' and the 'little sister' closer than assumed? Bioessays 29(11): 1105-1114 (2007). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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