c-Jun Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | c-Jun |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, primate, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | c-Jun is a component of the transcription factor AP-1, which binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73 (1,2). Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun-dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress-induced signaling pathways. The MAP kinase homologue SAPK/JNK binds to the amino-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun (3,4). c-Jun also plays a role in Neuropathi |
| Immunogen | Immunogen: Peptide derived from the amino-terminal sequence of human c-Jun |
| Other Names | [c-Jun; Transcription factor AP-1; transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog], [JUN; JUN; C-JUN; AP1] |
| Gene, Accession # | [c-Jun], Gene ID: 396913, NCBI: AAB50808.1 |
| Catalog # | MBS555002 |
| Price | $450 |
| Order / More Info | c-Jun Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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