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Antigenic Specificity | Phospho-ASK 1 (Ser83) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); ELISA (EIA); Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of ASK 1 (pSer83) in human samples. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response; which is essential for host defense against a wide range of pathogens. Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals; |
Immunogen | Immunogen: Synthesized peptide derived from human ASK 1 around the phosphorylation site of S83. AA range: 20-100 |
Other Names | [Apoptosis signal-regulating kinase 1; Mitogen-activated protein kinase kinase kinase 5; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5], [MAP3K5] |
Gene, Accession # | [ASK 1], Gene ID: 4217, NCBI: NP_005914.1, UniProt: Q99683 |
Catalog # | MBS846129 |
Price | $335 |
Order / More Info | Phospho-ASK 1 (Ser83) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |