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Antigenic Specificity | SYT5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.4 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SYT5 protein. Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules. May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca2+-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling co |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human Synaptotagmin V |
Other Names | [SytV; Synaptotagmin-5; synaptotagmin 5] |
Gene, Accession # | [SYT5], Gene ID: 6861, NCBI: NP_001284703.1, UniProt: O00445 |
Catalog # | MBS9414642 |
Price | $255 |
Order / More Info | SYT5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |