TRIM21 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TRIM21 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TRIM21 antibody is human specific. This antibody is predicted to not cross-react with TRIM6. TRIM21, a member of the tripartite motif (TRIM) family, is a part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus (1). RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus (2). TRIM21 also acts as a cytosolic antibody receptor; detection of intracellular antibodies activate immune signaling by stimulating the transcription factor pathways of NF-kappaB, AP-1, IRF3, IRF5, and IRF7, resulting in the production of proinflammatory cytokines and the induction of an antivira |
| Immunogen | Immunogen: TRIM21 antibody was raised against an 16 amino acid peptide near the center of human TRIM21. Buffer: TRIM21 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [TRIM21; SSA; RO52; SSA1; RNF81; Ro/SSA; E3 ubiquitin-protein ligase TRIM21; 52 kDa Ro protein; SS-A; tripartite motif containing 21], [TRIM21; TRIM21; SSA; RO52; SSA1; RNF81; Ro/SSA; RNF81; RO52; SSA1; SS-A] |
| Gene, Accession # | [TRIM21], Gene ID: 6737, NCBI: NP_003132, UniProt: P19474 |
| Catalog # | MBS153388 |
| Price | $375 |
| Order / More Info | TRIM21 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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