CD130/gp130 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD130/gp130
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: CD130/gp130 antibody detects endogenous levels of total CD130/gp130. Description: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors.Function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janu
ImmunogenImmunogen: A synthesized peptide derived from human CD130/gp130 Subcellular Location: Secreted and Cell Membrane. Tissue Specificity: Found in all the tissues and cell lines examined (PubMed:2261637). Expression not restricted to IL6 responsive cells (PubMed:2261637). Expressed in blood serum (at protein level) (PubMed:24629561). Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Zebrafish (86%), Bovine (100%), Horse (100%), Sheep (100%
Other Names[CD130; CD130 antigen; CDw130; gp130; GP130 RAPS; IL 6R beta; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6R-beta; IL-6RB; IL6 ST; IL6RB_HUMAN; IL6ST; Interleukin 6 receptor subunit beta; Interleukin receptor beta chain; Interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; Membrane glycoprotein 130; Membrane glycoprotein gp130; Oncostatin M receptor; Oncostatin M receptor alpha subunit; Oncostatin-M receptor subunit alpha]
Gene, Accession #[CD130/gp130], Gene ID: 3572, NCBI: NP_001177910.1, UniProt: P40189
Catalog #MBS9601867
Price$240, $280
Order / More InfoCD130/gp130 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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