Tip60 (Phospho-Ser90) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTip60 (Phospho-Ser90)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90. The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.Kamine J., Virology 216:357-366(1996).Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001).Legube G., Gene 310:161-168(2003).
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 90(P-G-S(p)-P-E) derived from Human Tip60.
Other Names[HTATIP; TI60; Tat-interactive protein-60]
Gene, Accession #[Tip60], Gene ID: 10524, NCBI: NP_001193762.1, UniProt: Q92993
Catalog #MBS9414780
Price$200, $255
Order / More InfoTip60 (Phospho-Ser90) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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