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Antigenic Specificity | Tip60 (Phospho-Ser90) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90. The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.Kamine J., Virology 216:357-366(1996).Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001).Legube G., Gene 310:161-168(2003). |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 90(P-G-S(p)-P-E) derived from Human Tip60. |
Other Names | [HTATIP; TI60; Tat-interactive protein-60] |
Gene, Accession # | [Tip60], Gene ID: 10524, NCBI: NP_001193762.1, UniProt: Q92993 |
Catalog # | MBS9414780 |
Price | $200, $255 |
Order / More Info | Tip60 (Phospho-Ser90) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |