Plexin-A1 (Sema Domain) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Plexin-A1 (Sema Domain) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Plexin-A1 (Sema Domain) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot, Immunocytochemistry, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects a 220 kDa* protein corresponding to the apparent molecular mass of Plexin-A1 on SDS-PAGE immunoblots of neonatal rat brain lysates and Cos-7 cells transfected with mouse Plexin-A1. Plexins are a family of large integral membrane proteins that complex with neuropilins to form semaphorin co-receptors. The extracellular region of plexins contains a semaphorin domain, multiple glycine-rich motifs, and MET-related sequences. The cytoplasmic region contains a Sex/Plexin domain and putative tyrosine phosphorylation sites that mediate signal transduction after activation. This region in Plexin-A1 binds the RhoGTPases, Rnd1 and RhoD. Recruitment of Rnd1 has been implicated in the cytoskeletal collapse that occurs after semaphori |
| Immunogen | Immunogen: Plexin-A1 synthetic peptide (coupled to carrier protein) corresponding to a region within the semaphorin domain in human Plexin-A1. This sequence is highly conserved in rat and mouse Plexin-A1, and has low homology to other Plexin family members. |
| Other Names | [Plexin A1 (Sema Domain); PLXN1; NOV], [PLXNA1; NOV; NOVP; PLXN1; PLEXIN-A1; DKFZp761P19121] |
| Gene, Accession # | Gene ID: 5361, NCBI: NP_115618.2, UniProt: Q6ZTY7 |
| Catalog # | MBS472054 |
| Price | $385 |
| Order / More Info | Plexin-A1 (Sema Domain) Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Takahashi, T. & Strittmatter, S.M. (2001) Neuron 29:429.• Tamagnone, L. et al. (1999) Cell 99:71. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies