CD54 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CD54 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Intercellular cell adhesion molecule-1 (CD54 or ICAM-1) is a cell surface glycoprotein that belongs to the immunoglobulin superfamily (IgSF) of adhesion molecules. CD54 is expressed at low levels in diverse cell types, and is induced by cytokines (TNF-alpha, interleukin-1) and bacterial lipopolysaccharide (1). Apical localization of CD54 on endothelial cells (or basolateral localization on epithelial cells) is a prerequisite for leukocyte trafficking through the endothelial (or epithelial) barrier (1). Apical expression of CD54 on epithelial cells mediates pathogen invasion as well as host defense, a pattern also observed in tumors (1). CD54 also functions as a co-stimulator on antigen presenting cells, binding to its receptor LFA-1 (leukoc |
| Immunogen | Immunogen: Recombinant protein of house mouseICAM1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CD54; Icam-1; Ly-47; MALA-2; MGC6195; Icam1] |
| Gene, Accession # | [CD54], Gene ID: 3383, NCBI: NP_000192.2, UniProt: P05362 |
| Catalog # | MBS8500410 |
| Price | $310 |
| Order / More Info | CD54 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hopkins, A. M. et al. (2004) Adv. Drug Deliv. Rev. 56, 763-778. 2. Nishibori, M. et al. (2003) J. Pharmacol. Sci. 92, 7-12. 3. Holland, J. and Owens, T. (1997) J. Biol. Chem. 272, 9108-9112. 4. Etienne, S. et al. (1998) J. Immunol. 161, 5755-5761. 5. Pluskota, E. et al. (2000) J. Biol. Chem. 275, 30029-30036. 6. Muro, S. et al. (2003) J. Cell Sci. 116, 1599-1609. 7. Wang, Q. et al. (2004) J. Biol. Chem. 278, 47731-47743. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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