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Antigenic Specificity | Human ERR GAMMA (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Paraffin* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects estrogen-related receptor gamma (ERR gamma), a member of the nuclear hormone receptor superfamily. The fasting-induced coactivator protein PGC-1a has been shown to activate the ERR gamma, and together these proteins have a major role in the regulation of ERR alpha gene expression and energy homeostasis. . . ERR gamma and alpha are co-expressed in high energy demanding tissues such as skeletal muscle heart and kidney, and have been suggested to function in their differentiation. . . ERR gamma has also been shown to be over-expressed in breast tumours, and has been suggested to be a potential biomarker for favourable clinical course and hormonal sensitivity. MBS222835 detects estrogen-related receptor gamma (ERR gamma), |
Immunogen | Immunogen: Synthetic peptide: N-terminal domain of human ERR gamma, conjugated to Keyhole Limpet Hemocyanin (KLH). Histology Positive Control Tissue: Kidney. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human ERR gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [estrogen-related receptor gamma isoform 2; Estrogen-related receptor gamma; estrogen-related receptor gamma; ERR gamma-2; estrogen receptor-related protein 3; nuclear receptor subfamily 3 group B member 3; estrogen-related receptor gamma; ERR gamma-2; Estrogen receptor-related protein 3; Nuclear receptor subfamily 3 group B member 3], [ESRRG; ESRRG; ERR3; NR3B3; ERRgamma; ERR3; ERRG2; KIAA0832; NR3B3] |
Gene, Accession # | [ERR GAMMA], Gene ID: 2104, NCBI: NP_001127757.1, UniProt: P62508 |
Catalog # | MBS222835 |
Price | $550 |
Order / More Info | Human ERR GAMMA (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |