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Antigenic Specificity | GFR alpha 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | DEAE purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GFR alpha 2 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently. NTNRalpha was also termed GDNFRβ, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRα-2 recently. GFRα-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRα-2, and t |
Immunogen | Immunogen: GFR alpha 2 antibody was raised against a 15 amino acid peptide near the center of human GFR alpha 2. Buffer: GFR alpha 2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [GFR alpha 2; NTNRA; RETL2; TRNR2; GDNFRB; NRTNR-ALPHA; GDNF family receptor alpha-2; GDNF receptor beta; GDNF receptor alpha-2; GDNF family receptor alpha 2], [GFRA2; GFRA2; NTNRA; RETL2; TRNR2; GDNFRB; NRTNR-ALPHA; GDNFRB; RETL2; TRNR2; GDNF receptor alpha-2; GDNFR-alpha-2; GFR-alpha-2; GDNFR-beta; NRTNR-alpha; NTNR-alpha] |
Gene, Accession # | [GFRA2], Gene ID: 2675, NCBI: AAC52036, UniProt: O00451 |
Catalog # | MBS151140 |
Price | $375 |
Order / More Info | GFR alpha 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |