AKT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKT
Clone10D6
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: AKT protein detects endogenous levels of AKT1. The serine-threonine protein kinase encoded by the AKT1 (AKT serine/threonine kinase 1) gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phospho
ImmunogenImmunogen: Synthetic Peptide of AKT at AA range of 400-480
Other Names[Mouse AKT Mouse (10D6); AKT1]
Gene, Accession #[AKT], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749
Catalog #MBS9700503
Price$130, $220, $325
Order / More InfoAKT Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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