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Antigenic Specificity | AKT |
Clone | 10D6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AKT protein detects endogenous levels of AKT1. The serine-threonine protein kinase encoded by the AKT1 (AKT serine/threonine kinase 1) gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phospho |
Immunogen | Immunogen: Synthetic Peptide of AKT at AA range of 400-480 |
Other Names | [Mouse AKT Mouse (10D6); AKT1] |
Gene, Accession # | [AKT], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749 |
Catalog # | MBS9700503 |
Price | $130, $220, $325 |
Order / More Info | AKT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |