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Antigenic Specificity | DUSP4 (C-term), 331-361 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DUSP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human DUSP4. DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, |
Immunogen | n/a |
Other Names | [Dual specificity protein phosphatase 4; Dual specificity protein phosphatase hVH2; Mitogen-activated protein kinase phosphatase 2; MAP kinase phosphatase 2; MKP-2; DUSP4; MKP2; VH2] |
Gene, Accession # | [DUSP4], Gene ID: 1846, NCBI: NP_001385.1, UniProt: Q13115 |
Catalog # | MBS9212644 |
Price | $165, $370 |
Order / More Info | DUSP4 (C-term), 331-361 Antibody from MYBIOSOURCE INC. |
Product Specific References | Chen, P., et al., J. Biol. Chem. 276(31):29440-29449 (2001). Smith, A., et al., Genomics 42(3):524-527 (1997). Chu, Y., et al., J. Biol. Chem. 271(11):6497-6501 (1996). King, A.G., et al., Oncogene 11(12):2553-2563 (1995). Guan, K.L., et al., J. Biol. Chem. 270(13):7197-7203 (1995). |