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Antigenic Specificity | alpha-SMA |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: alpha-SMA antibody detects endogenous levels of alpha-SMA. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. |
Immunogen | Immunogen: Synthetic peptide corresponding to N terminal residues of Human alpha smooth muscle Actin. |
Other Names | [ACTA2; Actsa; Actvs; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein] |
Gene, Accession # | Gene ID: 59, NCBI: NP_001135417.1, UniProt: P62736 |
Catalog # | MBS8511177 |
Price | $290 |
Order / More Info | alpha-SMA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |