Edit |   |
---|---|
Antigenic Specificity | G3BP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect G3BP in human, mouse and rat samples. Background: G3BP1 (GTPase activating protein (SH3 domain) binding protein 1), also known as G3BP or HDH-VIII, is a ubiquitously expressed protein that localizes to the cytoplasm in proliferating cells and to the nucleus in non-proliferating cells. One of several DNA-unwinding enzymes, G3BP1 functions as a sequence-specific, phosphorylation-dependent helicase that unwinds partial RNA and DNA duplexes containing hanging 3'- or 5'- ends. G3BP1 uses magnesium as a cofactor and, in addition to its helicase activity, acts as an endoribonuclease that cleaves mRNA between adenine and cytosine residues at the 3'-UTR. An element of the Ras signaling pathway, G3BP1 binds to the SH3 do |
Immunogen | Immunogen: Synthetic peptide at C-terminal. Positive Control: Western blot: Jurkat, 3T3, rat kidney cell lysate |
Other Names | [ATP-dependent DNA helicase VIII], [G3BP1; G3BP1; G3BP; HDH-VIII; G3BP; G3BP-1; hDH VIII] |
Gene, Accession # | [G3BP], Gene ID: 10146, NCBI: NP_005745.1, UniProt: Q13283 |
Catalog # | MBS840790 |
Price | $150, $325 |
Order / More Info | G3BP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |