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Antigenic Specificity | ITGB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed: 15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed: 11812992). Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediat |
Immunogen | Immunogen: Recombinant Human Integrin beta-2 protein (37-201AA) |
Other Names | [Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150; 95 subunit beta; Complement receptor C3 subunit beta; CD18; ITGB2; CD18; MFI7] |
Gene, Accession # | [ITGB2], Gene ID: 3689, NCBI: NP_000202.3, UniProt: P05107 |
Catalog # | MBS7048488 |
Price | $160, $235 |
Order / More Info | ITGB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |