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Antigenic Specificity | DAPK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death. |
Immunogen | Immunogen: Recombinant human Death-associated protein kinase 2 protein(222-370AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10084 / sc-10081 / sc-130734 |
Other Names | [DAP kinase 2; DAP-kinase-related protein 1; DRP-1; DAPK2], [DAPK2; DAPK2; DRP1; DRP-1; DAP kinase 2; DRP-1] |
Gene, Accession # | [DAPK2], Gene ID: 23604, NCBI: NP_055141.2, UniProt: Q9UIK4 |
Catalog # | MBS1493214 |
Price | $160, $235 |
Order / More Info | DAPK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |