APG8a/b (MAP1LC3A/B), 100-125 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | APG8a/b (MAP1LC3A/B), 100-125 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: bovine) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.29 |
| Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Cleaved-APG8a/b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-125 amino acids from human Cleaved-APG8a/b. The product of this gene is a subunit of neuronalmicrotubule-associated MAP1A and MAP1B proteins, which are involvedin microtubule assembly and important for neurogenesis. Studies onthe rat homolog implicate a role for this gene in autophagy, aprocess that involves the bulk degradation of cytoplasmiccomponent. |
| Immunogen | n/a |
| Other Names | [Microtubule-associated proteins 1A/1B light chain 3B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light chain 3 beta; MAP1LC3B; MAP1ALC3] |
| Gene, Accession # | [MAP1LC3B], Gene ID: 81631, NCBI: NP_073729.1, UniProt: Q9GZQ8 |
| Catalog # | MBS9214893 |
| Price | $165, $370 |
| Order / More Info | APG8a/b (MAP1LC3A/B), 100-125 Antibody from MYBIOSOURCE INC. |
| Product Specific References | References for protein 1.Rouschop, K.M., et al. J. Clin. Invest. 120(1):127-141(2010) 2.Kirkin, V., et al. Mol. Cell 33(4):505-516(2009) 3.Othman, E.Q., et al. J. Clin. Lab. Anal. 23(4):249-258(2009) 4.Liu, Q., et al. Ai Zheng 27(1):25-29(2008) 5.Komatsu, M., et al. Cell 131(6):1149-1163(2007) References for U251 cell line: 1. Westermark B.; Ponten J.; Hugosson R. (1973). Determinants for the establishment of permanent tissue culture lines from human gliomas. Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Ponten, J.,Westermark B. (1978). Properties of Human Malignant Glioma Cells in Vitro. Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.;Kohli L.; Klocke B.J.; Roth K.A.(2010). Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. Neuro Oncol. 12(5): 473-481.[ PMID: 20406898]. |
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MYBIOSOURCE INC.
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