NEUROD1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NEUROD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of total NEUROD1 antibody. NeuroD is a member of the basic helix-loop-helix (bHLH) family of transcription factors. These proteins function by forming heterodimers with E-proteins and binding to the canonical E-box sequence CANNTG (1,2). Neuronal activity results in CaMKII-mediated phosphorylation of NeuroD at Ser336, which is necessary for formation and growth of dendrites (3,4). NeuroD is also phosphorylated at Ser274 though the results are context dependent as phosphorylation by Erk stimulates NeuroD activity in pancreatic b-cells while phosphorylation by GSK-3b inhibits NeuroD in neurons (3). NeuroD is crucially important in both the pancreas and developing nervous system, and plays a large role in |
| Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human NEUROD1. |
| Other Names | [NEUROD1; BETA2; BHF-1; NEUROD; bHLHa3] |
| Gene, Accession # | [NEUROD1], Gene ID: 4760, NCBI: NP_002491.2, UniProt: Q13562 |
| Catalog # | MBS9412130 |
| Price | $255 |
| Order / More Info | NEUROD1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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