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Antigenic Specificity | SMAD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Smad4 Polyclonal Antibody detects endogenous levels of Smad4 protein. SMAD4 encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of SMAD4 forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to r |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Smad4 at AA range: 40-120 |
Other Names | [Rabbit Smad4; SMAD4; DPC4; MADH4; Mothers against decapentaplegic homolog 4; MAD homolog 4; Mothers against DPP homolog 4; Deletion target in pancreatic carcinoma 4; SMAD family member 4; SMAD 4; Smad4; hSMAD4] |
Gene, Accession # | [SMAD4], Gene ID: 4089, NCBI: NP_005350.1, UniProt: Q13485 |
Catalog # | MBS9700752 |
Price | $250, $250 |
Order / More Info | SMAD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |