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Antigenic Specificity | PABP2/ PABPN1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mL, 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also e |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human PABP2. |
Other Names | [PABP2 Mouse mAb; Nuclear poly(A)-binding protein 1; OPMD; PAB2; PABII; PABP-2; PABP2; poly(A) binding protein 2; poly(A) binding protein II; poly(A) binding protein, nuclear 1; poly(A)-binding protein 2; Poly(A)-binding protein II; Polyadenylate-binding nuclear protein 1; Polyadenylate-binding protein 2], [mPABII; OPMD; PAB2; PABII; PABP-2; PABP2; Pabp3; PABPN1] |
Gene, Accession # | [PABP2/PABPN1], Gene ID: 8106, NCBI: NP_001347480.1, UniProt: Q86U42 |
Catalog # | MBS435140 |
Price | $225, $350, $565 |
Order / More Info | PABP2/ PABPN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |