PABP2/ PABPN1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPABP2/ PABPN1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size0.02 mL, 0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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DescriptionThis gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also e
ImmunogenSource Note: This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human PABP2.
Other Names[PABP2 Mouse mAb; Nuclear poly(A)-binding protein 1; OPMD; PAB2; PABII; PABP-2; PABP2; poly(A) binding protein 2; poly(A) binding protein II; poly(A) binding protein, nuclear 1; poly(A)-binding protein 2; Poly(A)-binding protein II; Polyadenylate-binding nuclear protein 1; Polyadenylate-binding protein 2], [mPABII; OPMD; PAB2; PABII; PABP-2; PABP2; Pabp3; PABPN1]
Gene, Accession #[PABP2/PABPN1], Gene ID: 8106, NCBI: NP_001347480.1, UniProt: Q86U42
Catalog #MBS435140
Price$225, $350, $565
Order / More InfoPABP2/ PABPN1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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