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Antigenic Specificity | SSB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SSB antibody detects endogenous levels of total SSB. Function: Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597).Subunit Structure: Interacts with DDX15. May interact with RUFY1.Post-translational Modifications: Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein. The N-terminus is blocked. |
Immunogen | Immunogen: A synthesized peptide derived from human SSB Subcellular Location: Nucleus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (92%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%) |
Other Names | [Autoantigen La; La; La autoantigen; La autoantigen homolog; La protein; La ribonucleoprotein; La ribonucleoprotein domain family member 3; LA_HUMAN; LARP3; Lupus La antigen; Lupus La protein; Lupus La protein homolog; MGC118101; MGC93380; mRNA for autoantigen; OTTMUSP00000014043; RP23 273G23.1; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B (autoantigen La); Sjogren syndrome antigen B; SS B; SS-B; SS-B/La protein; SSB] |
Gene, Accession # | [SSB], Gene ID: 6741, NCBI: NP_001281074.1, UniProt: P05455 |
Catalog # | MBS9608779 |
Price | $240, $280 |
Order / More Info | SSB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |